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Novo Nordisk has also cited indirect comparison data suggesting that fewer patients discontinued oral semaglutide due to side effects compared with orforglipron, though the companies and independent commentators note the significant methodological limitations of such comparisons in the absence of a head-to-head obesity trial

Note on allergies and sensitivities: If one has a true milk allergy, all dairy products need to be avoided, including the products containing Proserum

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Occasional vomiting can occur, especially if you eat too quickly or consume large portions while your gastric emptying is slowed

It was designed for short-term use, typically 12 weeks or less, because sustained stimulant exposure raises the risk of tolerance, dependency, and cardiovascular complications